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There’s nothing quite like the comforting aroma of a hot, bubbling casserole on a cold winter evening—and this John Wayne Casserole delivers all that and more. Named after the legendary cowboy actor, this dish is as bold and satisfying as the man himself.
I first discovered this savory delight in my grandmother’s recipe box, scribbled on a faded notecard with “Dad’s Favorite” written at the top. My Nonna wasn’t one for Western movies, but she did appreciate a hearty casserole that could feed the family with leftovers to spare. And once I gave it a try myself, I knew this would become one of my go-to winter dishes—meaty, cheesy, and utterly delicious.
This recipe combines layers of seasoned ground beef, rich vegetables, and a fluffy biscuit base, all smothered in gooey cheddar cheese and sour cream. It’s comfort food, American-style, with just the right hint of spice and creaminess to make every bite unforgettable.
Why You’ll Love This John Wayne Casserole
- Hearty & Filling: With ground beef, cheese, and biscuit layers, it’s the ultimate meal in one dish.
- Family Favorite: Kids and adults alike love the flavor-packed layers.
- Perfect for Winter: Warm, cheesy, and comforting—ideal for chilly evenings.
- Great Leftovers: It reheats beautifully for a quick lunch the next day.
Ingredients (Serves 6)

Biscuit Layer
- 1 can (16 oz) refrigerated biscuit dough (or homemade biscuits)
Beef Layer
- 1 lb ground beef
- 1 medium yellow onion, diced
- 1 bell pepper (red or green), chopped
- 1 packet taco seasoning (or 2 tbsp homemade mix)
- ½ cup water
Creamy Layer
- ½ cup sour cream
- ½ cup mayonnaise
- 1 cup shredded cheddar cheese
- 1 can (4 oz) diced green chilies (optional for a kick)
Toppings
- 1 ½ cups shredded cheddar or Mexican blend cheese
- Sliced jalapeños or green onions (optional garnish)
Instructions
Step 1: Preheat & Prepare
Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish with cooking spray or butter.
Step 2: Layer the Biscuits
Press the biscuit dough into the bottom of your prepared baking dish. Use your fingers to press the dough slightly up the sides, forming a shallow crust. Bake for 8–10 minutes, just until slightly puffed but not fully cooked.
Step 3: Cook the Ground Beef
While the crust bakes, cook the ground beef in a large skillet over medium heat until browned, about 6–8 minutes. Drain any excess fat. Add diced onion, bell pepper, and taco seasoning. Stir in water and simmer until the vegetables soften and the mixture thickens—about 5 minutes.
Step 4: Make the Creamy Mixture
In a medium bowl, combine sour cream, mayonnaise, 1 cup of cheddar cheese, and the green chilies. Stir until smooth.
Step 5: Layer the Casserole
- Spread the seasoned beef mixture over the partially baked biscuit layer.
- Spoon the creamy sour cream mixture over the beef.
- Top everything with the remaining shredded cheese.
Step 6: Bake
Return the dish to the oven and bake uncovered for 25–30 minutes, until the cheese is bubbly and golden.
Step 7: Garnish & Serve
Let it rest for 5 minutes before slicing. Garnish with sliced jalapeños or chopped green onions if desired. Serve warm!
Serving Tips
- Pair it with a crisp green salad or roasted veggies to balance the richness.
- Add a side of guacamole or salsa for a Tex-Mex flair.
- Want to make it spicier? Stir a dash of cayenne into the beef or add hot sauce to the creamy layer.
Storage & Reheating
Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat individual portions in the microwave or warm the entire dish in a 300°F oven for 15–20 minutes.
Make It Your Own
The beauty of John Wayne Casserole is its flexibility. Here are a few variations to try:
- Vegetarian Twist: Replace ground beef with black beans and corn for a meatless version.
- Breakfast Version: Use breakfast sausage and scramble in eggs before layering with cheese.
- Extra Crunch: Sprinkle crushed tortilla chips on top for added texture.
Wrapping It Up
Whether you’re hosting a casual dinner or just want a cozy, family-friendly meal, John Wayne Casserole is sure to become a regular in your winter recipe rotation. It’s rich, satisfying, and a little nostalgic—a tribute to the American spirit in every forkful.
So next time you’re craving something hearty, give this cowboy-approved casserole a try. And don’t forget to save a slice for tomorrow—it’s even better the next day!
Have You Tried It?
We’d love to hear how your John Wayne Casserole turned out! Did you add your own twist or stick with the classic? Share your tips and photos in the comments below!

John Wayne Casserole
Equipment
- Skillet
- 9×13-inch baking dish
- mixing bowls
- oven
Ingredients
- Biscuit Layer:
- 1 can 16 oz refrigerated biscuit dough
- Beef Layer:
- 1 lb ground beef
- 1 medium yellow onion diced
- 1 bell pepper red or green, chopped
- 1 packet taco seasoning
- ½ cup water
- Creamy Layer:
- ½ cup sour cream
- ½ cup mayonnaise
- 1 cup shredded cheddar cheese
- 1 can 4 oz diced green chilies (optional)
- Toppings:
- 1½ cups shredded cheddar or Mexican blend cheese
- Optional: sliced jalapeños or green onions
Instructions
- Preheat oven to 350°F (175°C). Grease a 9×13-inch casserole dish.
- Layer biscuits into the dish, pressing to form a crust. Prebake for 8–10 minutes until slightly puffed.
- Cook beef in a skillet over medium heat until browned. Drain excess fat. Add onion, bell pepper, taco seasoning, and water. Simmer until thickened.
- Mix creamy layer in a bowl: sour cream, mayo, cheese, and green chilies. Stir until smooth.
- Layer the casserole: spread beef over the biscuit crust, then top with creamy mixture, and finish with shredded cheese.
- Bake uncovered for 25–30 minutes, until cheese is melted and bubbly.
- Rest for 5 minutes before serving. Garnish with sliced jalapeños or green onions if desired.
Notes
- Want a little extra heat? Add cayenne pepper or hot sauce to the beef.
- For a vegetarian option, swap beef for black beans and corn.
- Leftovers reheat beautifully—store in the fridge for up to 3 days.